human SPRY4 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SPRY4

Gene Name

sprouty RTK signaling antagonist 4

Gene ID

81848

Gene Synonyms

HH17

ORF Size

900 bp

RefSeq#

NM_030964

Gene Description

SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS; MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002 (PubMed 12027893)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.323308

HGNC ID

HGNC:15533