human SPIRE1 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SPIRE1

Gene Name

spire type actin nucleation factor 1

Gene ID

56907

Gene Synonyms

Spir-1

ORF Size

1794 bp

RefSeq#

NM_020148

Gene Description

Spire proteins, such as SPIRE1, are highly conserved between species. They belong to the family of Wiskott-Aldrich homology region-2 (WH2) proteins, which are involved in actin organization (Kerkhoff et al., 2001 (PubMed 11747823)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.515283

HGNC ID

HGNC:30622