human SNRPA shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SNRPA

Gene Name

small nuclear ribonucleoprotein polypeptide A

Gene ID

6626

Gene Synonyms

Mud1; U1-A; U1A

ORF Size

849 bp

RefSeq#

NM_004596

Gene Description

SNRPA associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.

UniGene ID

Hs.466775

HGNC ID

HGNC:11151