human SNAI2 shRNA silencing Adenovirus

Product Info

Knockdown

>60% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SNAI2

Gene Name

snail family transcriptional repressor 2

Gene ID

6591

Gene Synonyms

SLUG; SLUGH1; SNAIL2; WS2D

ORF Size

807 bp

RefSeq#

NM_003068

Gene Description

SNAI2 encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

UniGene ID

Hs.360174

HGNC ID

HGNC:11094