human SLC18A1 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SLC18A1

Gene Name

solute carrier family 18 member A1

Gene ID

6570

Gene Synonyms

CGAT; VAT1; VMAT1

ORF Size

1158 bp

RefSeq#

NM_003053

Gene Description

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (Peter et al., 1993 (PubMed 7905859)). See also SLC18A2 (MIM 193001).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.158322

HGNC ID

HGNC:10934