human SLC17A8 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SLC17A8

Gene Name

solute carrier family 17 member 8

Gene ID

246213

Gene Synonyms

DFNA25; VGLUT3

ORF Size

1620 bp

RefSeq#

NM_139319

Gene Description

SLC17A8 encodes a vesicular glutamate transporter. The encoded protein transports the neurotransmitter glutamate into synaptic vesicles before it is released into the synaptic cleft. Mutations in this gene are the cause of autosomal-dominant nonsyndromic type 25 deafness. Alternate splicing results in multiple transcript variants.

UniGene ID

Hs.116871

HGNC ID

HGNC:20151