human SH2B3 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-222878
Availability:
3-5 weeks
Name:
Ad-h-SH2B3-shRNA
This is an Adenovirus expressing shRNA for silencing of Human SH2B3.
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Product Info
- Knockdown
- >80% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SH2B3
- Gene Name
- SH2B adaptor protein 3
- Gene ID
- 10019
- Gene Synonyms
- IDDM20; LNK
- ORF Size
- 1728 bp
- RefSeq#
- NM_005475
- Gene Description
- SH2B3 encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.
- UniGene ID
- Hs.506784
- HGNC ID
- HGNC:29605
Related Products
Product | Cat No. |
---|---|
AAV-h-SH2B3 | AAV-222878 |
AAV-m-SH2B3 | AAV-271875 |
Ad-h-SH2B3 | ADV-222878 |
Ad-m-SH2B3 | ADV-271875 |
AAV-h-SH2B3-shRNA | shAAV-222878 |
AAV-m-SH2B3-shRNA | shAAV-271875 |
Ad-m-SH2B3-shRNA | shADV-271875 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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