human SGPP1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SGPP1

Gene Name

sphingosine-1-phosphate phosphatase 1

Gene ID

81537

Gene Synonyms

SPPase1

ORF Size

1326 bp

RefSeq#

NM_030791

Gene Description

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 (PubMed 10859351); Le Stunff et al., 2007 (PubMed 17895250)).(supplied by OMIM, Jun 2009)

UniGene ID

Hs.24678

HGNC ID

HGNC:17720