human SGCB shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SGCB

Gene Name

sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)

Gene ID

6443

Gene Synonyms

A3b; LGMD2E; SGC

ORF Size

957 bp

RefSeq#

NM_000232

Gene Description

SGCB encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.

UniGene ID

Hs.438953

HGNC ID

HGNC:10806