human RHOQ shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-221188
Availability:
3-5 weeks
Name:
Ad-h-RHOQ-shRNA
This is an Adenovirus expressing shRNA for silencing of Human RHOQ.
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Product Info
- Knockdown
- >80% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- RHOQ
- Gene Name
- ras homolog family member Q
- Gene ID
- 23433
- Gene Synonyms
- ARHQ; HEL-S-42; RASL7A; TC10; TC10A
- ORF Size
- 618 bp
- RefSeq#
- NM_012249
- Gene Description
- RHOQ encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14.
- UniGene ID
- Hs.709193
- HGNC ID
- HGNC:17736
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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