human RAB3GAP1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

RAB3GAP1

Gene Name

RAB3 GTPase activating protein catalytic subunit 1

Gene ID

22930

Gene Synonyms

P130; RAB3GAP; RAB3GAP130; WARBM1

ORF Size

2808 bp

RefSeq#

NM_012233

Gene Description

RAB3GAP1 encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.

UniGene ID

Hs.306327

HGNC ID

HGNC:17063