human RAB18 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

RAB18

Gene Name

RAB18, member RAS oncogene family

Gene ID

22931

Gene Synonyms

RAB18LI1; WARBM3

ORF Size

621 bp

RefSeq#

NM_021252

Gene Description

RAB18 is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene.

UniGene ID

Hs.406799

HGNC ID

HGNC:14244