human PQBP1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PQBP1

Gene Name

polyglutamine binding protein 1

Gene ID

10084

Gene Synonyms

MRX2; MRX55; MRXS3; MRXS8; NPW38; RENS1; SHS

ORF Size

798 bp

RefSeq#

NM_005710

Gene Description

PQBP1 encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked mental retardation. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

UniGene ID

Hs.534384

HGNC ID

HGNC:9330