human POLR2L shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

POLR2L

Gene Name

RNA polymerase II subunit L

Gene ID

5441

Gene Synonyms

hRPB7.6; RBP10; RPABC5; RPB10; RPB10beta; RPB7.6

ORF Size

204 bp

RefSeq#

NM_021128

Gene Description

POLR2L encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains four conserved cysteines characteristic of an atypical zinc-binding domain. Like its counterpart in yeast, this subunit may be shared by the other two DNA-directed RNA polymerases.

UniGene ID

Hs.441072

HGNC ID

HGNC:9199