human PLK4 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PLK4

Gene Name

polo like kinase 4

Gene ID

10733

Gene Synonyms

MCCRP2; SAK; STK18

ORF Size

2913 bp

RefSeq#

NM_014264

Gene Description

PLK4 encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

UniGene ID

Hs.172052

HGNC ID

HGNC:11397