human PISD shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PISD

Gene Name

phosphatidylserine decarboxylase

Gene ID

23761

Gene Synonyms

DJ858B16; dJ858B16.2; PSD; PSDC; PSSC

ORF Size

1128 bp

RefSeq#

NM_014338

Gene Description

Phosphatidylserine decarboxylases (PSDs; EC 4.1.1.65) catalyze the formation of phosphatidylethanolamine (PE) by decarboxylation of phosphatidylserine (PS). Type I PSDs, such as PISD, are targeted to the inner mitochondrial membrane by an N-terminal targeting sequence. PISD also contains a conserved LGST motif that functions as an autocatalytic cleavage site where the proenzyme is split into mature alpha and beta subunits (Schuiki and Daum, 2009 (PubMed 19165886)).(supplied by OMIM, Jul 2010)

UniGene ID

Hs.420559

HGNC ID

HGNC:8999