human PIK3CD shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PIK3CD

Gene Name

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

Gene ID

5293

Gene Synonyms

APDS; IMD14; p110D; P110DELTA; PI3K

ORF Size

3135 bp

RefSeq#

NM_005026

Gene Description

Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.

UniGene ID

Hs.518451

HGNC ID

HGNC:8977