human PIGW shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PIGW

Gene Name

phosphatidylinositol glycan anchor biosynthesis class W

Gene ID

284098

Gene Synonyms

Gwt1; HPMRS5

ORF Size

1512 bp

RefSeq#

NM_178517

Gene Description

Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol (Murakami et al., 2003 (PubMed 14517336)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.378885

HGNC ID

HGNC:23213