human PECI shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ECI2

Gene Name

enoyl-CoA delta isomerase 2

Gene ID

10455

Gene Synonyms

ACBD2; dJ1013A10.3; DRS-1; DRS1; HCA88; PECI

ORF Size

1095 bp

RefSeq#

NM_006117

Gene Description

ECI2 encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described.

UniGene ID

Hs.15250

HGNC ID

HGNC:14601