human PDXP shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PDXP

Gene Name

pyridoxal phosphatase

Gene ID

57026

Gene Synonyms

CIN; dJ37E16.5; PLP

ORF Size

891 bp

RefSeq#

NM_020315

Gene Description

Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al., 2003 (PubMed 14522954)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.632762

HGNC ID

HGNC:30259