human PDE9A shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PDE9A

Gene Name

phosphodiesterase 9A

Gene ID

5152

Gene Synonyms

HSPDE9A2

ORF Size

1602 bp

RefSeq#

NM_001001567

Gene Description

PDE9A catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene.

UniGene ID

Hs.473927

HGNC ID

HGNC:8795