human PAX1 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PAX1

Gene Name

paired box 1

Gene ID

5075

Gene Synonyms

HUP48; OFC2

ORF Size

1323 bp

RefSeq#

NM_006192

Gene Description

PAX1 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. PAX1 plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. PAX1 is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations.

UniGene ID

Hs.349082

HGNC ID

HGNC:8615