human OTC shRNA silencing Adenovirus

Cat. No: shADV-217979

Availability: 5-8 weeks

Name: Ad-h-OTC-shRNA

This is an Adenovirus expressing shRNA for silencing of Human OTC.

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Species: Human
Gene Symbol: OTC
Gene Name: ornithine carbamoyltransferase
Gene ID: 5009
Gene Synonyms: OCTD
ORF Size: 1065 bp
RefSeq#: NM_000531
Gene Description: This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
UniGene ID: Hs.117050
HGNC ID: HGNC:8512