human NR4A2 shRNA silencing Adenovirus

Product Info

Knockdown

>50% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

NR4A2

Gene Name

nuclear receptor subfamily 4 group A member 2

Gene ID

4929

Gene Synonyms

HZF-3; NOT; NURR1; RNR1; TINUR

ORF Size

1608 bp

RefSeq#

NM_006186

Gene Description

NR4A2 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

UniGene ID

Hs.563344

HGNC ID

HGNC:7981