human NR4A1 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

NR4A1

Gene Name

nuclear receptor subfamily 4 group A member 1

Gene ID

3164

Gene Synonyms

GFRP1; HMR; N10; NAK-1; NGFIB; NP10; NUR77; TR3

ORF Size

1797 bp

RefSeq#

NM_002135

Gene Description

NR4A1 encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.524430

HGNC ID

HGNC:7980