human NFE2L2 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

NFE2L2

Gene Name

nuclear factor, erythroid 2 like 2

Gene ID

4780

Gene Synonyms

HEBP1; NRF2

ORF Size

1818 bp

RefSeq#

NM_006164

Gene Description

NFE2L2 encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.715540

HGNC ID

HGNC:7782