human NCKIPSD shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

NCKIPSD

Gene Name

NCK interacting protein with SH3 domain

Gene ID

51517

Gene Synonyms

AF3P21; DIP; DIP1; ORF1; SPIN90; VIP54; WASLBP; WISH

ORF Size

2148 bp

RefSeq#

NM_016453

Gene Description

NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding distinct isoforms have been identified.

UniGene ID

Hs.655006

HGNC ID

HGNC:15486