human NAMPT shRNA silencing Adenovirus

Product Info

Knockdown

>60% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

NAMPT

Gene Name

nicotinamide phosphoribosyltransferase

Gene ID

10135

Gene Synonyms

1110035O14Rik; PBEF; PBEF1; VF; VISFATIN

ORF Size

1476 bp

RefSeq#

NM_005746

Gene Description

NAMPT encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. NAMPT has a pseudogene on chromosome 10.

UniGene ID

Hs.489615

HGNC ID

HGNC:30092