human MYL12B shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MYL12B

Gene Name

myosin light chain 12B

Gene ID

103910

Gene Synonyms

MLC-B; MRLC2

ORF Size

519 bp

RefSeq#

NM_033546

Gene Description

The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 (PubMed 11942626)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.464472

HGNC ID

HGNC:29827