human MYB shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MYB

Gene Name

MYB proto-oncogene, transcription factor

Gene ID

4602

Gene Synonyms

c-myb; c-myb_CDS; Cmyb; efg

ORF Size

1923 bp

RefSeq#

NM_005375

Gene Description

MYB encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.

UniGene ID

Hs.654446

HGNC ID

HGNC:7545