human MGEA5 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MGEA5

Gene Name

meningioma expressed antigen 5 (hyaluronidase)

Gene ID

10724

Gene Synonyms

MEA5; NCOAT; OGA

ORF Size

2550 bp

RefSeq#

NM_012215

Gene Description

The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 (PubMed 11148210)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.500842

HGNC ID

HGNC:7056