human MED21 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MED21

Gene Name

mediator complex subunit 21

Gene ID

9412

Gene Synonyms

hSrb7; SRB7; SURB7

ORF Size

435 bp

RefSeq#

NM_004264

Gene Description

The Mediator is a multiprotein coactivator that is required by DNA-binding transcription factors for transcriptional activation of polymerase II (see MIM 180660)-transcribed genes. MED21 is a Mediator subunit predicted to reside in the middle module and appears to be a core subunit found in nearly all Mediator preparations (summary by Sato et al., 2004 (PubMed 15175163)).(supplied by OMIM, Nov 2010)

UniGene ID

Hs.286145

HGNC ID

HGNC:11473