human MCOLN3 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MCOLN3

Gene Name

mucolipin 3

Gene ID

55283

Gene Synonyms

TRP-ML3; TRPML3

ORF Size

966 bp

RefSeq#

NM_018298

Gene Description

MCOLN3 encodes one of members of the mucolipin cation channel proteins. Mutation studies of the highly similar protein in mice have shown that the protein is found in cochlea hair cells, and mutant mice show early-onset hearing loss and balance problems. Multiple transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.535239

HGNC ID

HGNC:13358