human MARK2 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MARK2

Gene Name

microtubule affinity regulating kinase 2

Gene ID

2011

Gene Synonyms

EMK-1; EMK1; PAR-1; Par-1b; Par1b

ORF Size

2175 bp

RefSeq#

NM_004954

Gene Description

MARK2 encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.567261

HGNC ID

HGNC:3332