human MARCKSL1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MARCKSL1

Gene Name

MARCKS like 1

Gene ID

65108

Gene Synonyms

F52; MACMARCKS; MLP; MLP1; MRP

ORF Size

588 bp

RefSeq#

NM_023009

Gene Description

MARCKSL1 encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10.

UniGene ID

Hs.707012

HGNC ID

HGNC:7142