human MAPKAPK2 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MAPKAPK2

Gene Name

mitogen-activated protein kinase-activated protein kinase 2

Gene ID

9261

Gene Synonyms

MAPKAP-K2; MK-2; MK2

ORF Size

1203 bp

RefSeq#

NM_032960

Gene Description

MAPKAPK2 encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene.

UniGene ID

Hs.713747

HGNC ID

HGNC:6887