human MAPK11 shRNA silencing Adenovirus

Cat. No: shADV-214968

Availability: 3-5 weeks

Name: Ad-h-MAPK11-shRNA

This is an Adenovirus expressing shRNA for silencing of Human MAPK11.

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Species: Human
Gene Symbol: MAPK11
Gene Name: mitogen-activated protein kinase 11
Gene ID: 5600
Gene Synonyms: p38-2; P38B; p38Beta; P38BETA2; PRKM11; SAPK2; SAPK2B
ORF Size: 1095 bp
RefSeq#: NM_002751
Gene Description: MAPK11 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.
UniGene ID: Hs.57732
HGNC ID: HGNC:6873