human MAP4K5 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MAP4K5

Gene Name

mitogen-activated protein kinase kinase kinase kinase 5

Gene ID

11183

Gene Synonyms

GCKR; KHS; KHS1; MAPKKKK5

ORF Size

2541 bp

RefSeq#

NM_006575

Gene Description

MAP4K5 encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

UniGene ID

Hs.130491

HGNC ID

HGNC:6867