human MAP3K14 shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MAP3K14

Gene Name

mitogen-activated protein kinase kinase kinase 14

Gene ID

9020

Gene Synonyms

FTDCR1B; HS; HSNIK; NIK

ORF Size

2844 bp

RefSeq#

NM_003954

Gene Description

MAP3K14 encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.

UniGene ID

Hs.404183

HGNC ID

HGNC:6853