human KLF2 shRNA silencing Adenovirus

Product Info

Knockdown

>70% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

KLF2

Gene Name

Kruppel like factor 2

Gene ID

10365

Gene Synonyms

LKLF

ORF Size

1068 bp

RefSeq#

NM_016270

Gene Description

Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 (PubMed 19592277)).(supplied by OMIM, Feb 2011)

UniGene ID

Hs.715677

HGNC ID

HGNC:6347