human KDM1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

KDM1A

Gene Name

lysine demethylase 1A

Gene ID

23028

Gene Synonyms

AOF2; BHC110; CPRF; KDM1; LSD1

ORF Size

2631 bp

RefSeq#

NM_015013

Gene Description

KDM1A encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants.

UniGene ID

Hs.656420

HGNC ID

HGNC:29079