human IRGM shRNA silencing Adenovirus

Product Info

Knockdown

shRNA screening service available, please inquire about this service or other options.

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

IRGM

Gene Name

immunity related GTPase M

Gene ID

345611

Gene Synonyms

IFI1; IRGM1; LRG-47; LRG47

ORF Size

537 bp

RefSeq#

NM_001145805

Gene Description

IRGM encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.

UniGene ID

Hs.652148

HGNC ID

HGNC:29597