human IRF8 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-212413
Availability:
3-5 weeks
Name:
Ad-h-IRF8-shRNA
This is an Adenovirus expressing shRNA for silencing of Human IRF8.
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Product Info
- Knockdown
- >60% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- IRF8
- Gene Name
- interferon regulatory factor 8
- Gene ID
- 3394
- Gene Synonyms
- H-ICSBP; ICSBP; ICSBP1; IMD32A; IMD32B; IRF-8
- ORF Size
- 1281 bp
- RefSeq#
- NM_002163
- Gene Description
- Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
- UniGene ID
- Hs.137427
- HGNC ID
- HGNC:5358
Related Products
Product | Cat No. |
---|---|
AAV-h-IRF8 | AAV-212413 |
AAV-m-IRF8 | AAV-262374 |
Ad-h-IRF8 | ADV-212413 |
Ad-m-IRF8 | ADV-262374 |
AAV-h-IRF8-shRNA | shAAV-212413 |
AAV-m-IRF8-shRNA | shAAV-262374 |
Ad-m-IRF8-shRNA | shADV-262374 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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