human INPPL1 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

INPPL1

Gene Name

inositol polyphosphate phosphatase like 1

Gene ID

3636

Gene Synonyms

OPSMD; SHIP2

ORF Size

3777 bp

RefSeq#

NM_001567

Gene Description

INPPL1 is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.

UniGene ID

Hs.523875

HGNC ID

HGNC:6080