human IL10RB shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

IL10RB

Gene Name

interleukin 10 receptor subunit beta

Gene ID

3588

Gene Synonyms

CDW210B; CRF2-4; CRFB4; D21S58; D21S66; IL-10R2

ORF Size

978 bp

RefSeq#

NM_000628

Gene Description

IL10RB belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.

UniGene ID

Hs.654593

HGNC ID

HGNC:5965