human IKBKB shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

IKBKB

Gene Name

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

Gene ID

3551

Gene Synonyms

FLJ33771; FLJ36218; FLJ38368; FLJ40509; IKK-beta; IKK2; IKKB; MGC131801; NFKBIKB;

ORF Size

1263 bp

RefSeq#

NM_001556

Gene Description

IKBKB phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.

UniGene ID

Hs.597664

HGNC ID

HGNC:5960