human IGF2BP1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

IGF2BP1

Gene Name

insulin like growth factor 2 mRNA binding protein 1

Gene ID

10642

Gene Synonyms

CRD-BP; CRDBP; IMP-1; IMP1; VICKZ1; ZBP1

ORF Size

1734 bp

RefSeq#

NM_006546

Gene Description

IGF2BP1 encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.144936

HGNC ID

HGNC:28866