human IER3 shRNA silencing Adenovirus

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

IER3

Gene Name

immediate early response 3

Gene ID

8870

Gene Synonyms

DIF-2; DIF2; GLY96; IEX-1; IEX-1L; IEX1; PRG1

ORF Size

471 bp

RefSeq#

NM_003897

Gene Description

IER3 functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein.

UniGene ID

Hs.591785

HGNC ID

HGNC:5392