human HTATSF1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

HTATSF1

Gene Name

HIV-1 Tat specific factor 1

Gene ID

27336

Gene Synonyms

dJ196E23.2; TAT-SF1; TATSF1

ORF Size

2268 bp

RefSeq#

NM_014500

Gene Description

HTATSF1 functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.

UniGene ID

Hs.204475

HGNC ID

HGNC:5276