human HSPE1 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

HSPE1

Gene Name

heat shock protein family E (Hsp10) member 1

Gene ID

3336

Gene Synonyms

CPN10; EPF; GROES; HSP10

ORF Size

309 bp

RefSeq#

NM_002157

Gene Description

HSPE1 encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. HSPE1 and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.

UniGene ID

Hs.1197

HGNC ID

HGNC:5269